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KMID : 1188320090030020141
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Gut and Liver
2009 Volume.3 No. 2 p.141 ~ p.144
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A Case of Acute Q Fever with Severe Acute Cholestatic Hepatitis
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Choi Hyun-Cheul
Lee Sang-Hyub
Kim Jung-Hee
Kim Sung-Han
Hwang Jin-Hyeok
Kim Jin-Wook
Jeong Sook-Hyang
Kim Hae-Ryoung
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Abstract
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Minimal hepatic dysfunction can be common in acute Q fever, but severe acute cholestatic hepatitis is rarely reported. We report on a 55-year-old male with acute Q fever and severe acute cholestatic hepatitis. He complained of fever, jaundice, ascites, and restlessness on admission. A liver biopsy revealed the presence of compact fibrin-ring granulomas. Serologic titers for C. burnetii IgM and IgG were 2048:1 and 1024:1, respectively. C. burnetii DNA was detected by a nested polymerase chain reaction on the liver tissue.
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KEYWORD
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Acute Q fever, Fibrin-ring granuloma, Severe cholestatic hepatitis
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